A mutation in the general membrane trafficking machinery and hydrocephaly
نویسندگان
چکیده
منابع مشابه
A mutation in the general membrane trafficking machinery and hydrocephaly.
M embrane fusion is required to deliver specific cargo molecules to distinct intracellular compartments, thereby maintaining the functional and structural organization of eukaryotic cells, as well as intercellular communication, which occurs in precisely timed spatial patterns at the plasma membrane. During embryogenesis, exocytosis is harnessed to induce differentiation and morphogenesis, as d...
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The SNARE Machinery Is Involved in Apical Plasma Membrane Trafficking in MDCK Cells
We have investigated the controversial involvement of components of the SNARE (soluble N-ethyl maleimide-sensitive factor [NSF] attachment protein [SNAP] receptor) machinery in membrane traffic to the apical plasma membrane of polarized epithelial (MDCK) cells. Overexpression of syntaxin 3, but not of syntaxins 2 or 4, caused an inhibition of TGN to apical transport and apical recycling, and le...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2004
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0308601101